QPR manager Harry Redknapp is hoping Bobby Zamora can manage more than 45 minutes against Manchester United as fellow striker Loic Remy struggles with a groin complaint.
Rock-bottom Rangers are seven points adrift of safety in the Barclays Premier League heading into tomorrow's match with Sir Alex Ferguson's league leaders.
With 12 matches remaining, victory would be huge for QPR but an already unenviable task has been made more difficult by a lack of attacking options.
Deadline-day moves for Peter Crouch and Peter Odemwingie fell short, meaning Zamora and Remy are the men charged with shooting QPR to survival.
However, both are struggling with injury and Redknapp today revealed the latter almost certainly faces surgery on a long-standing hip complaint.
Zamora has made four substitute appearances since returning from a two-and-a-half-month spell on the sidelines and has not played more than 45 minutes in a match since the 1-0 defeat to Arsenal on October 27.
"Maybe Bobby will need an operation at the end of the season," Redknapp said. "I am not sure, he probably will do.
"The aim is to keep him going for the last 12 games of the season if we can because he is that important to us.
"We'll see how we go tomorrow with him. The longer we can get out of Bobby, the better.
"We're hoping we can get more than just half a game from him. It is up to the fitness people and the physios to try and push him on to longer if we can."
Zamora's condition means he is unlikely to be able to play more than a bit-part role until the end of the season, making Remy's return to fitness even more important.
The 26-year-old has made just two appearances since joining from Marseille, with a groin complaint still proving problematic.
"Remy has trained the last couple of days and looks okay," Redknapp said. "Whether he is fit for 90 minutes, we'll have to see how he goes today.
"He had a little bit of a setback after the Swansea game but he trained yesterday so we've got to see how he is.
"It is difficult with groins because you don't want to risk him and then he doesn't play for six or seven weeks because he tears it.
"We have got to see how he is and then make a decision on if he can play or how much he can play."
While Remy is a doubt, Redknapp can call on Junior Hoilett and Samba Diakite again.
It is a match QPR have spent the past two weeks preparing for, with part of that period spent in Dubai at a warm-weather training camp.
United have played twice in that period and head to Loftus Road without Wayne Rooney due to illness - not that Redknapp thinks that will impact them too much.
"They're full of quality players so whoever Alex picks they will be strong," he said.
"It is a big game for us tomorrow. We've got to be at it and give everything we've got to try and get a win."