David Moyes must decide whether to include Wayne Rooney in his Manchester United starting line-up to face Chelsea at Old Trafford on Monday.
The England forward was introduced as a substitute in last week's win at Swansea and after a further week's training could come into contention to face the club who have already had two bids for him turned down.
Rafael (hamstring) is out for up to four weeks, with Nani (groin), Ashley Young (ankle) and Javier Hernandez (hamstring) also not expected to be involved.
Chelsea defender David Luiz is doubtful for Monday's Barclays Premier League clash with Manchester United as Jose Mourinho bids to strike an early blow in the title race.
Brazilian centre-back Luiz has a hamstring problem and missed the first two Premier League fixtures of the season, against Hull and Aston Villa, but could return at Old Trafford or for next Friday's UEFA Super Cup clash with Bayern Munich in Prague.
Mourinho could rotate his options, with Romelu Lukaku in line to start up front. Defender Tomas Kalas suffered a fractured leg in pre-season and is out.
Man United: De Gea, Lindegaard, Smalling, Jones, Ferdinand, Vidic, Evans, Evra, Buttner, Fabio, Zaha, Valencia, Carrick, Cleverley, Anderson, Giggs, Lingard, Januzaj, Welbeck, Rooney, Van Persie.
Chelsea: Cech, Schwarzer, Hilario, Ivanovic, Cole, Luiz, Cahill, Terry, Azpilicueta, Bertrand, Mikel, Essien, Oscar, Ramires, Lampard, Van Ginkel, Hazard, Mata, Moses, Schurrle, De Bruyne, Torres, Lukaku, Ba.