Manchester City midfielder David Silva could return in Sunday's derby against Manchester United in the Premier League after two games out with a thigh injury.
Right-back Micah Richards (hamstring) is back in training after missing the start of the season and could be in contention but left-back Gael Clichy is not yet ready to feature.
Captain Vincent Kompany came through his comeback unscathed in midweek but fellow-centre back Martin Demichelis (knee) is a long-term casualty.
David Moyes looks set to plunge Nemanja Vidic and Rio Ferdinand into their third match in a week when Manchester United visit Manchester City.
The pair have not operated in tandem three times in such quick succession since 2010 but Moyes seems certain to stick with them, having already done so for the victories over Crystal Palace and Bayer Leverkusen.
Rafael (hamstring), Danny Welbeck (knee) and Phil Jones (ankle) all missed the midweek Champions League win, while Nani is available after suspension.
Man City: Hart, Pantilimon, Zabaleta, Richards, Kompany, Nastasic, Lescott, Boyata, Kolarov, Silva, Nasri, Milner, Navas, Fernandinho, Toure, Garcia, Rodwell, Aguero, Dzeko, Negredo, Jovetic.
Manchester United: De Gea, Lindegaard, Amos, Rafael, Fabio, Jones, Smalling, Ferdinand, Vidic, Evra, Buttner, Valencia, Giggs, Carrick, Cleverley, Fellaini, Anderson, Kagawa, Nani, Young, Welbeck, Van Persie, Rooney, Hernandez.