Left-back Danny Rose is likely to make his return from a toe injury in Tottenham's game against Chelsea on Saturday.
Defender Younes Kaboul (adductor) is doubtful, but midfielder Etienne Capoue remains sidelined with an ankle injury.
Spurs will give winger Aaron Lennon (foot) a fitness test on Friday while striker Emmanuel Adebayor is out through illness.
Chelsea will wait to determine whether midfielder Ramires is fit for Saturday's London derby at Tottenham.
The Brazilian suffered a hip injury in Tuesday night's Capital One Cup win at Swindon and was taken off at half-time, but Jose Mourinho hopes to include him in a much-changed line-up at White Hart Lane.
Ramires had replaced Marco van Ginkel, who is out for six months after undergoing knee surgery to repair a torn anterior cruciate ligament.
Spurs: Lloris, Friedel, Gomes, Walker, Naughton, Dawson, Kaboul, Vertonghen, Chiriches, Fryers, Rose, Sandro, Dembele, Eriksen, Paulinho, Holtby, Townsend, Lennon, Chadli, Sigurdsson, Lamela, Soldado, Defoe, Kane.
Chelsea: Cech, Schwarzer, Ivanovic, Cole, Luiz, Cahill, Terry, Azpilicueta, Bertrand, Ramires, Essien, Lampard, Oscar, Mikel, De Bruyne, Hazard, Willian, Mata, Schurrle, Torres, Ba, Eto'o.