Razvan Rat is doubtful with a hamstring injury sustained on international duty with Romania for when West Ham host Chelsea in the Premier League on Saturday.
Rat's fellow defenders Joey O'Brien and James Collins (both hamstring) are expected to be fit despite withdrawing from duty with the Republic of Ireland and Wales through injury.
Winston Reid (ankle) could be fit and George McCartney (knee) is back in training, but Andy Carroll (heel), Mladen Petric (thigh), Matthew Taylor (thigh) and Alou Diarra (both knee) are absent.
Left-back Ashley Cole is in the squad for Chelsea's Premier League match at West Ham despite being substituted while on England duty with a recurrence of a rib injury.
Striker Fernando Torres is back in training following an adductor injury sustained in training at the start of the month, but is not yet ready to return.
Midfielder Marco van Ginkel, who is out long-term with a knee injury, is the only absentee.
West Ham Squad: Jaaskelainen, Adrian, Demel, O'Brien, Rat, Collins, Tomkins, McCartney, Potts, Ruddock, Diame, Nolan, Noble, Collison, Downing, J Cole, Morrison, Jarvis, Maiga, C Cole.
Chelsea squad: Cech, Ivanovic, Cole, Luiz, Essien, Ramires, Lampard, Mata, Oscar, Mikel, Schurrle, De Bruyne, Hazard, Ba, Willian, Schwarzer, Cahill, Terry, Azpilicueta, Eto'o, Bertrand, Kalas, Beeney.