Jose Mourinho plans to rotate his squad throughout December after witnessing Chelsea's less than convincing progress to the Champions League knockout stages.
The Blues were beaten 1-0 by Basle, who claimed the double over the 2012 European champions, but advanced to the last 16 as Schalke drew 0-0 at Steaua Bucharest.
Chelsea play the Romanians on December 11 bidding to confirm top spot in Group E, something which eluded them in Switzerland as Mohamed Salah's strike settled a match in which Mourinho's men failed to muster a meaningful shot.
The limp loss was all the more surprising after the impressive display at West Ham, but Mourinho had made just one change from Upton Park.
It is likely he will regularly rotate his options next month, with Sunday's Premier League contest with Southampton the first of nine matches in a congested period.
"Clearly I got signs of fatigue," Mourinho said.
"I got signs of players in trouble to play two consecutive matches in three days.
"That will push me, for sure, to make different kinds of decisions. That's obvious.
"In some positions we have that situation resolved in a very easy way because we have lots of players to play the attacking positions on the right, on the left, behind the striker.
"We'll make decisions, again not to punish players, because I don't punish players when I'm not upset and when I've found a reason for a not-good performance.
"It's not a question of punishment, it's a question of using the squad and the options we have and to make changes when we have so many consecutive matches."