Dani Osvaldo will be missing for Southampton's FA Cup fourth-round clash with Yeovil after the striker was given a two-week ban by the club following a training ground altercation.
The 28 year-old Italian is alleged to have head-butted team-mate Jose Fonte during a training ground fight this week.
He was due to return to the squad after serving a three-game suspension but will now sit out another three Saints fixtures as a result of the Italy international's involvement in the fracas.
With a Premier League clash with Arsenal on Tuesday night, Southampton are likely to rotate their team but there will definitely be no place for Dejan Lovren, Gaston Ramirez (both ankle) or Victor Wanyama (calf).
Southampton squad: Boruc, Clyne, Fonte, Shaw, Schneiderlin, Davis, Cork, Lallana, Rodriguez, Lambert, Davis, Yoshida, Ward-Prowse, Do Prado, Hooiveld, Chambers, Gallagher.