Captain Nemanja Vidic returns from suspension for Manchester United's game against Aston Villa on Saturday.
Striker Robin van Persie is out with a knee injury.
Centre-backs Chris Smalling (hamstring) and Jonny Evans (calf) are doubts.
Aston Villa midfielder Karim El Ahmadi is a doubt for Saturday's Barclays Premier League clash with Manchester United at Old Trafford due to a thigh problem.
The injury forced El Ahmadi to come off in the first half of the 4-1 home loss to Stoke last Sunday and Villa boss Paul Lambert has said the Morocco international is "struggling" ahead of the trip to Manchester.
Forward Andreas Weimann had to depart the field around the same time in the Stoke match because of a dead leg but is expected to be available.
Man United: De Gea, Lindegaard, Rafael, Evra, Ferdinand, Smalling, Vidic, Jones, Evans, Buttner, Giggs, Carrick, Young, Cleverley, Fletcher, Valencia, Kagawa, Nani, Fellaini, Januzaj, Mata, Rooney, Welbeck, Hernandez.
Aston Villa:: Guzan, Steer, Clark, Baker, Luna, Vlaar, Bennett, Lowton, Bertrand, Bacuna, Albrighton, Westwood, Delph, Sylla, Tonev, Holt, Helenius, Weimann, Agbonlahor, Benteke.