Oldham boss Dave Penney is likely to hand debuts to goalkeeper Darryl Flahavan and left-back Lee Hills when his side host Leeds in the first round of the FA Cup.
The duo arrived on loan from Crystal Palace this week and will go straight into Penney's squad to face the League One leaders.
Alan Sheehan has returned to Leeds following a loan spell at Boundary Park but will not feature for Simon Grayson's men.
The Latics have no suspension worries ahead of the game but could be without Alex Marrow, Pawel Abbott and Chris Taylor, who are all carrying knocks.
Penney told Press Association Sport: "There are two or three that are struggling but we're touching wood that they will be okay."
Luciano Becchio could make a surprise return to action for Leeds.
The Argentinian, who injured his ankle against Charlton at the beginning of October, has missed the last five matches and although manager Simon Grayson has given no clues, a fully-fit Becchio would solve a striker crisis.
Sam Vokes, on loan from Wolves, has partnered Jermaine Beckford in recent weeks, but he and Leicester winger Max Gradel are both cup-tied, while Tresor Kandol starts a three-game ban after accepting a charge of violent conduct.
That leaves American Mike Grella and Enoch Showunmi to vie for a place alongside Beckford unless Becchio recovers in time for the tie, which will be the first game screened live by the Football Association on their website, www.thefa.com.
Grayson is not expected to make too many changes after his side's two successive 4-0 wins, but Neil Kilkenny is pushing for a recall after impressing as a second-half substitute against Yeovil.
Goalkeeper Shane Higgs (thigh), Ben Parker, Andy Robinson (both hamstring) and Rui Marques (Achilles) have struggled with injury in recent weeks.