Uruguay coach Oscar Tabarez admitted he warned his side about the potential of a World Cup upset against Costa Rica.
Despite taking a first-half lead through Edinson Cavani's penalty the South American's conceded twice in eight minutes to Arsenal's 21-year-old midfielder Joel Campbell and Oscar Duarte's first international goal.
Substitute Marcos Urena added a late third before frustration got the better of Maxi Pereira who was sent off in added time for a wild hack at Campbell.
"This can happen to any team, we had talked about this topic after what happened to Spain (who lost 5-1 to Holland)," Tabarez told his post-match press conference.
"Neither team can believe that there are things that cannot happen.
"I don't know what Costa Rica's limit is but today they played well.
"They were tactically better than us, which reflects well on their coach and players.
"When they took the lead, they gave us space and let us play where we couldn't do them any harm.
"Now we're going to try and get back on track against England."