There will be some well established stars, but here our experts take a look at those younger players who will be looking to prove their credentials.
Michael Cox - Zonal Marking
Juan Cuadrado had an exceptional season at Fiorentina and should shine on Colombia's right wing. A direct, tricky and now goalscoring outside-right. 26 now, but still relatively unheralded.
Will Unwin - ITV.com
Serge Aurier: In this era of every player needing to be able to attack, this man is one of the most potent players around, and also very adept at defending too.
Kristan Heneage - Freelance football writer
Raphael Varane: France has needed a calming influence at the back and Varane could be just that man. Composure personified, the Real Madrid defender could be a deciding factor in France's tournament.
Ollie Irish - ITV.com
Paul Pogba: The 21-year-old France midfielder, who got away from Man Utd, shone for Juventus this season. He could become the best central midfielder in the world before he's 25.
Nick Ames - Freelance football journalist
Raheem Sterling: The England forward's improvement in the last nine months makes you wonder exactly what else he is capable of. If we don't know, it's likely the Italians, Uruguayans and Costa Ricans won't have much of an idea either - and he could well prove Roy Hodgson's trump card in Group D.
Jack Pitt-Brooke - The Independent
Koke: If Spain need more youth and legs in midfield, it will come from Atletico Madrid's brilliant 22-year-old, the long-term heir to Xavi.