Mark Pougatch is joined by Ian Wright, Ryan Giggs and Lee Dixon in the studio as England attempt to finish their group campaign in style against Lithuania at the LFF Stadium in Vilnius.
England's qualification for the 2018 World Cup is already secure following last Thursday's victory against Slovenia.
Jermain Defoe scored his 20th international goal as England overcame stubborn opposition to win 2-0 when the sides met at Wembley earlier this year.
Commentary comes from Clive Tyldesley and former England manager Glenn Hoddle.
Coverage starts on ITV and ITV Hub at 4.30pm.
Gary Cahill spoke to Gabriel after the Slovenia game about the experience of the players in the England side right now.
Kyler Walker speaks to Gabriel Clarke after England saw off Slovenia in injury time.
Gareth Southgate reflects after the final whistle on taking England to the World Cup in Russia next year.
Harry Kane and Joe Hart spoke to Gabriel Clarke after the final whistle against Slovenia.
Harry Kane fired England to next summer's World Cup but his last-gasp winner cannot paper over the cracks after Gareth Southgate's men limped to victory against limited Slovenia.
Mark Pougatch is joined by Ryan Giggs, Ian Wright and Lee Dixon for England vs Slovenia at Wembley live on ITV as the Three Lions look to qualify for the 2018 World Cup in Russia.
England manager Gareth Southgate says the win over Slovakia was the most satisfying of his tenure as Three Lions manager so far.
Watch the full interview below: