The death of 25-year-old Peaches Geldof is another tragedy to hit the family - 14 years after her mother Paula Yates died.
Peaches was 11 when the former Big Breakfast presenter died from an accidental heroin overdose in 2000 at the age of 41.
Two years earlier, Yates had lost custody of her daughter and her sisters Pixie and Fifi - who went to live with their father Sir Bob Geldof - after an apparent suicide attempt.
Sir Bob also later took custody of Yates' daughter Tiger Lily after the deaths of both her mother and father INXS frontman Michael Hutchence, who was found dead in a Sydney hotel room in 1997.
Peaches told Elle magazine in an interview in November 2012 of her struggles to get over her parents' split - the couple divorced when she was seven-years-old - and her mother's death.
I was completely aware of the whole situation, the transition of my mother who was amazing, who wrote books on parenting, who gave us this idyllic childhood in Kent; and who then turned into this heartbroken shell of a woman who was just medicating to get through the day. On top of that, there was my father who was very embittered and depressed. It was like living on a permanent see-saw and very scary and sad. Those feelings have always stayed with me, they just never went away.
Peaches' husband Thomas Cohen said he would bring up their two boys - 23-month-old Astala and 11-month-old Phaedra - "with their mother in their hearts".