Sir Elton John has vowed never to wear Dolce and Gabbana ever again after comments the duo reportedly made about IVF in an interview with an Italian magazine.
Domenico Dolce and Stefano Gabbana talked about their private life and the importance of families in an interview with Panorama.
In the interview, the pair said: "We oppose gay adoptions. The only family is the traditional one.
"No chemical offsprings and rented uterus: life has a natural flow, there are things that should not be changed.
Dolce added that procreation "must be an act of love", saying: "You are born to a mother and a father – or at least that’s how it should be.
"I call children of chemistry, synthetic children. Uteri [for] rent, semen chosen from a catalog."
Sir Elton, who is married to David Furnish, responded on Instagram, writing: "How dare you refer to my beautiful children as "synthetic".
"And shame on you for wagging your judgmental little fingers at IVF - a miracle that has allowed legions of loving people, both straight and gay, to fulfill their dream of having children.
"Your archaic thinking is out of step with the the times, just like your fashions.
"I shall never wear Dolce and Gabanna ever again. #BoycottDolceGabanna.
Sir Elton wasn't the only well-known face to respond to the interview.
Former tennis star Martina Navratilova, who recently married her long term partner Julia Lemigova in New York, took to Twitter to protest about the comments.
Stefano Gabbana later took to his Instagram to respond to Sir Elton's comments.
Posting up an image from 1994, the designer wrote: "We live in a democratic country and respect for the ideas of others is essential".