Mexican authorities have released CCTV of the moment infamous drug lord 'El Chapo' escaped from prison - for the second time.

National Security Commissioner Monte Alejandro Rubido said security forces were hard at work to find the drug kingpin, whose real name is Joaquin Guzman.

Rubido showed a press conference grainy video of a dressed Guzman pacing the room, looking behind the partition wall by his shower and toilet, sitting on his bed, then crouching again behind the wall, where he finally disappeared from view at 8:52 p.m. local time.

He changed his shoes, and went to the shower.

Monte Alejandro Rubido, National Security Commissioner
The hole through which El Chapo escaped. Credit: RTV

The partition wall blocked the camera's view of a roughly 50-cm (20 inch) by 50-cm entrance hole to the mile-long tunnel Guzman used to escape. It was one of two blind spots for the security cameras in Guzman's cell.

The tunnel El Chapo used to escape. Credit: APTN

The escape of Guzman, Mexico's most notorious drug lord, is a major embarrassment for President Enrique Pena Nieto, and was the second time the drug kingpin had broken out of prison.

Guzman puts on his shoes before disappearing. Credit: RTV

Up until his departure, Guzman's behaviour had been 'normal' for a person who spent many hours in a small cell, Rubido said. The commissioner said the blind spots were designed to permit Guzman some privacy while he was washing.

The video footage showed the partition wall was high enough to cover the lower half of Guzman's body while standing. The jail break occurred just as Pena Nieto began a four-day state visit to France. Guzman's first jail break was in 2001.