Former Manchester United defender Gary Neville has been appointed as Valencia's head coach until the end of the season.
The English assistant will work alongside brother Phil at the Mestalla after coach Nuno quit last week.
The Spanish side are owned by Peter Lim who also has a stake in Salford City.
Neville will be part of the England coach staff during Euro 2016 in France next summer.
Valencia will present their new head coach at a press conference on Thursday. Neville's first game in charge will be next week against Lyon in the Champions League, leaving brother Phil in caretaker charge for this weekend's clash with Barcelona.
Neville said: “I am absolutely thrilled to be given this opportunity with Valencia. Valencia are a huge football club of immense standing and I know from my time as a player the passion and dedication of the Valencia fans.
“I am really looking forward to working with the club’s talented group of players and am excited about the challenge ahead.”
Neville has left his role as a Sky Sports pundit with immediate effect.
England manager Roy Hodgson has praised Neville's decision to start his managerial career abroad.
“I'm delighted that Gary has decided to take this excellent opportunity. It's the right moment in time for him and I'm 100 per cent behind his decision to join Valencia as the new head coach.
“As far as I’m concerned, this will be an extra string to his bow and the experience he will gain working in the Spanish league can only be beneficial to our work together with the England team.
“Gary’s commitment to The FA’s preparations for Euro 2016 will not be in any way affected by the fact that he will be coaching abroad during the next five months.
"As someone who has spent a large part of my coaching career working abroad, I salute his decision and hope he gains as much from his time in Spain as I have done from the various countries which I have worked.
"I wish him and his brother Phil the very best of luck as they prepare for their first match versus Lyon in the Champions League."