Homer Simpson will take questions from fans live on air in an animated television first this year.
Motion capture technology will allow Dan Castellaneta - the actor who has played Homer since 1989 - to perform in real-time during a Simpsons episode in May.
Producer Al Jean, told CNNMoney:
Dan Castellaneta will be in the studio and not only what he says will go out live, but the motions he makes will be incorporated in what Homer does on screen.
The show will be simultaneously broadcast across the US and the three-minute-long live part of the cartoon comedy will look identical to the normal show.
"He'll be saying something current like, 'can you believe Donald Trump shot a man today' or whatever is going on," said Mr Jean.
"As far as I know, this is the first time it's been done by any animated show."
Using the hashtag #HomerLive, fans will be encouraged to ask the world's favourite yellow oaf questions he could answer during the segment, scheduled for 15 May.
The Simpsons was first broadcast in 1989 and has since become the longest-running animated show in television history.