Thousands of junior doctors in England are set to take industrial action in an ongoing dispute over the new junior doctors' contract which the Government has signalled it intends to impose.
The doctors are to withdraw full labour over the two-day strike.
Here is what you need to know:
What does 'full withdrawal of labour' mean?
Junior doctors in England are withdrawing emergency care - the first time such a step has been taken during a strike
This means junior doctors will be walking out of A+E units, urgent maternity services, resuscitation and mental health crisis teams
The walkout is planned from 8am to 5pm on Tuesday and Wednesday
What effect has this latest action had on NHS services?
According to figures from NHS England, 112,856 outpatient appointments have been cancelled
12,711 planned operations have been cancelled and will need to be rearranged
Across the country, consultants who would normally be staffing clinics and planned operations will be moving to other areas of hospitals to provide cover
The BMA says emergency care will be provided by senior doctors
Those with long-term health conditions should be prepared - there are a range of other primary care services that can offer help, such as your pharmacist, dentist or optician
If you have a planned operation, procedure or outpatient appointment on a day when industrial action is taking place, your hospital will contact you if the appointment needs to be rearranged
If you are unsure, contact your hospital
Patients already in hospital will continue to receive normal care
Your GP may be busier than usual over the period of industrial action
Accident and Emergency departments will be open to deal with serious and life-threatening conditions - only those with genuine emergency needs should visit A+E
Why are junior doctors striking again?
The main point of disagreement with the contract has been over weekend pay and whether Saturdays should attract extra "unsocial" payments
The BMA has rejected the offer and urged Jeremy Hunt to reduce the offer of a basic pay rise and instead have better premium rates on Saturdays
The BMA says the government's intention to impose the contract has left junior doctors with no choice but to take industrial action
What is the Government's response to the latest strike?
Health secretary Jeremy Hunt has called the strike "risks the safety of many patients", and said the action was "extreme" and has urged the BMA to call off the industrial action