The remainder of Didcot power station could be demolished as early as this weekend, ITV News understands.
Explosive charges are believed to have been set, and families have been told that the demolition could take place on Saturday or Sunday.
ITV News Wales and West of England Correspondent Rupert Evelyn tweeted:
RWE Npower, which owns the plant, said in a letter to local residents and businesses: "On 11 July our contractor will begin to prepare the building for the controlled explosive demolition.
"This process will take around up to two weeks. We will give 48 hours’ notice of the exact date and approximate timing of demolition."