A rare 'supermoon' will appear 14% bigger and 30% brighter on Monday, in an event described by Nasa as "undeniably beautiful".
In the UK, people will see the moon rise above rooftops in the closest encounter for 69 years.
At 11.23am (UK time), the gap between the moon and the Earth will be at its shortest point - known as "perigee" - a distance of 221,525 miles.
However sky watchers will have to wait until 5pm to see the moon emerge in all its glory.
People will then be able to see the moon take on a "low-hanging" effect, where it will give an optical illusion of being close to the horizon.
The last time the moon was this close to the Earth was in 1948, and will not be this close until November 25 2034.
What is a supermoon?
'Supermoons' are often spectacular occurrences.
They take place when a close approach to Earth is accompanied by a full moon.
High and low tides - which are affected by the gravity of the moon - are expected to rise, but only by a small amount.
Monday's event is expected to be the biggest and brightest in a series of three 'supermoons'.
The first was on October 16, and the third will be on December 14.