West Ham vs Chelsea, Saturday 9th December, 3pm:
Joe Hart is set to drop to the bench while Winston Reid, Javier Hernandez and Andy Carroll should be back in the West Ham squad for the visit of Chelsea.
Spanish goalkeeper Adrian impressed when deputising for Hart against his parent club Manchester City last weekend and he is poised to keep his place.
Midfielder Danny Drinkwater is out of Chelsea's Premier League trip to West Ham after missing three days' training through illness.
Defender David Luiz remains out with a knee injury and Chelsea boss Antonio Conte is reluctant to put a timescale on his absence.
Huddersfield vs Brighton, Saturday 9th December, 3pm
Huddersfield head coach David Wagner is expected to choose from an unchanged squad for the home game against Brighton.
Centre-half Martin Cranie is hoping to recover from an ankle knock and Wagner has no new injury or suspension worries following last week's defeat at Everton.
Brighton can report no fresh injury problems ahead of the trip to West Yorkshire.
Burnley vs Watford, Saturday 9th December, 3pm
Burnley's Robbie Brady is set for a six-month lay-off following a knee injury, with Scott Arfield the likeliest beneficiary this weekend.
Ben Mee is a doubt after a knock required stitches above the knee, Matt Lowton looks set to miss a third game and Dean Marney, Jon Walters (both knee) and Tom Heaton (shoulder) are all recovering.
Watford manager Marco Silva will take a late decision on the fitness of Miguel Britos ahead of his side's Premier League trip to Burnley on Saturday.
Tottenham vs Stoke City, Saturday 9th December, 3pm
Tottenham defender Davinson Sanchez is suspended for Saturday's Premier League game at home to Stoke.
Sanchez is serving the first part of a three-match ban following his red card against Watford last weekend.
Toby Alderweireld and Victor Wanyama remain out with hamstring and knee injuries respectively.
Stoke will be without Bruno Martins Indi and Jese Rodriguez for Saturday's Premier League trip to Wembley to face Tottenham.
Martins Indi could be sidelined for eight weeks with the groin injury he suffered in last weekend's victory over Swansea while Jese has had to rush home to Gran Canaria to be with his seriously ill baby son.
Swansea vs West Brom, Saturday 9th December, 3pm
Federico Fernandez is set to sit out Swansea's home game against West Brom.
Fernandez has missed the last three games after returning home to Argentina following the death of his father and, although he played an hour for the Under-23s on Thursday night, he is more likely to return against Manchester City next week.
Chris Brunt and Matt Phillips are expected to return to the West Brom squad this weekend for the trip Wales.
Crystal Palace vs Bournemouth, Saturday 9th December, 3pm
Wayne Hennessey is fit to return to Crystal Palace when they host Bournemouth. The Wales international has shaken off a back problem but faces competition from Julian Speroni, who impressed in the goalless draw at West Brom
Bournemouth will be without Adam Smith for their Premier League trip to Crystal Palace on Saturday.
Defender Smith is serving a one-match suspension after picking up his fifth yellow card of the season against Southampton.
Newcastle vs Leicester, Saturday 9th December, 5:30pm
Newcastle skipper Jamaal Lascelles has provided manager Rafael Benitez with a major boost ahead of Saturday's Premier League clash with Leicester.
The central defender, who has missed the last four games with a foot injury, is available once again, as is winger Christian Atsu after shaking off a groin problem.
Leicester have no new injury problems ahead of their trip to the north east.
Southampton vs Arsenal, Sunday 10th December, 12pm
Cedric Soares is out of Southampton's Premier League clash with Arsenal on Sunday.
The full-back will miss the visit of the Gunners due to a hamstring injury suffered in the recent 2-1 loss at Manchester City.
Arsenal are sweating over the fitness of Shkodran Mustafi ahead of Sunday's Premier League trip to Southampton. The defender was forced off early on in last weekend's defeat to Manchester United and could be out of the St Mary's clash with a thigh problem.
Liverpool vs Everton, Sunday 10th December, 2:15pm
Liverpool left-back Alberto Moreno could be sidelined for potentially up to six weeks with an ankle injury.
The defender will be assessed by a second specialist over the weekend but the fear is the problem, sustained in Wednesday's 7-0 win over Spartak Moscow, could keep him out until the new year.
Phil Jagielka is set to return to the Everton squad for Sunday's Merseyside derby at Anfield.
The defender missed the Premier League victories over West Ham and Huddersfield but is fit again, although he and Michael Keane may have to settle for spots on the bench after back-to-back clean sheets.
Manchester United vs Manchester City, Sunday 10th December, 4:30pm
Manchester United midfielder Paul Pogba starts a three-match ban as bitter rivals Manchester City arrive on Sunday.
Zlatan Ibrahimovic, Phil Jones and Nemanja Matic are available for the derby, while midfielder Marouane Fellaini will be assessed ahead of the game.
Manchester City playmaker David Silva is fit for Sunday's derby at Manchester United but captain Vincent Kompany is doubtful.