Fulham v Watford - Saturday 12:30pm
Fulham will be without Tom Cairney and Neeskens Kebano for Saturday's Premier League clash with Watford at Craven Cottage. Cairney continues to nurse a foot concern, with Kebano still unable to shake off an ankle problem.
Defender Tim Ream is back in training after a thigh injury but will not be fully fit in time to feature against the Hornets.
Watford reported no fresh injury problems ahead of the game.
Winger Gerard Deulofeu is closing in on a return to full training after an abdominal problem, but will not be rushed into what would be a first appearance of the season.
Midfielder Nathaniel Chalobah played for the under-23s side earlier in the week to continue his recovery from a serious knee injury, so could be on the bench again, but Tom Cleverley (Achilles) remains a long-term absentee.
Fulham squad: Bettinelli, Odoi, Le Marchand, Fosu-Mensah, Mawson, McDonald, Schurrle, Seri, Zambo, Mitrovic, Vietto, Fabri, Chambers, Christie, Bryan, Sessegnon, Johansen, Kamara.
Watford Squad: Foster, Janmaat, Cathcart, Holebas, Kabasele, Doucoure, Hughes, Capoue, Pereyra, Deeney, Gray, Gomes, Mariappa, Masina, Kiko, Sema, Chalobah, Success
Burnley v Bournemouth - Saturday 3:00pm
Burnley will be without defender Ben Gibson for the Premier League clash against Bournemouth at Turf Moor.
Gibson has undergone minor hernia surgery and is set to be sidelined for several weeks.
Midfielder Steven Defour and winger Robbie Brady continued their comebacks from long-term absences with appearances in a game at the training ground on Thursday but are not yet ready for the first team.
Bournemouth defender Charlie Daniels and midfielder Kyle Taylor are both fitness doubts ahead of their trip north.
Left-back Daniels has been sidelined by a knee injury, while Taylor has picked up a calf problem so continues to be assessed.
Winger Junior Stanislas made a welcome return from a serious knee injury with a run-out in the Hampshire Senior Cup on Tuesday, so could feature in the squad.
Burnley squad: Hart, Heaton, Lowton, Taylor, Tarkowski, Mee, Ward, Bardsley, Long, Cork, Gudmundsson, Hendrick, Westwood, Lennon, McNeil, Vokes, Barnes, Wood, Vydra.
Bournemouth squad: Begovic, S Cook, Ake, A Smith, Rico, Gosling, Lerma, Brooks, Fraser, Wilson, King, Boruc, Francis, Surman, Ibe, L Cook, Mousset, Defoe, Daniels, Taylor, Stanislas.
Cardiff City v Manchester City - Saturday 3:00pm
Neil Warnock will make a late call on the Cardiff side to take on Premier League champions Manchester City at home.
The Cardiff manager says has to assess "one or two niggles" picked up in training, as well as the effects of a virus which has affected the camp this week.
On-loan midfielder Harry Arter should be fit after being forced off by illness at Chelsea last weekend, but Aron Gunnarsson misses out again after suffering another knock in training.
Pep Guardiola will be without full-back Benjamin Mendy for the Champions' trip to south Wales. The Frenchman also missed City's Champions League defeat to Lyon with a foot injury
Other than Kevin De Bruyne, who is stepping up his recovery from a knee injury, Guardiola should have a full strength squad to choose from.
Cardiff squad: Etheridge, Smithies, Peltier, Richards, Cunningham, Morrison, Bamba, Connolly, Manga, Bennett, Arter, Damour, Ralls, Camarasa, Paterson, Hoilett, Murphy, Reid, Zohore, Ward, Madine.
Crystal Palace v Newcastle - Saturday 3:00pm
Christian Benteke will be Crystal Palace's only significant absentee when they host Newcastle in the Premier League on Saturday.
The striker remains sidelined with a knee injury so Jordan Ayew is expected to continue to deputise.
Scott Dann and Connor Wickham continue their recoveries from long-term knee injuries.
Newcastle skipper Jamaal Lascelles is fit to take his place in the squad for the trip to Selhurst Park.
Defender Lascelles did not reappear for the second half of last weekend's 2-1 home defeat to Arsenal after aggravating an ankle problem in the warm-up, but he is back in training and available for the visit to Selhurst Park.
Midfielder Jonjo Shelvey was not risked against the Gunners after returning to the bench following a lay-off with a thigh injury, but has trained all week and only defender Florian Lejeune (knee ligaments) is missing.
Crystal Palace squad: Hennessey, Guaita, Speroni, Wan-Bissaka, Ward, Tomkins, Sakho, Kelly, Van Aanholt, Souare, Townsend, Kouyate, McArthur, Meyer, Milivojevic, Puncheon, Riedewald, Schlupp, Ayew, Kaikai, Sorloth, Zaha.
Newcastle squad: Dubravka, Darlow, Yedlin, Dummett, Manquillo, Sterry, Lascelles, Clark, Fernandez, Schar, Shelvey, Hayden, Diame, Ki, Ritchie, Kenedy, Murphy, Atsu, Longstaff, Perez, Rondon, Muto, Joselu.
Leicester City v Huddersfield Town - Saturday 3:00pm
Leicester will be without captain Wes Morgan for their home game against Huddersfield.
Morgan is suspended after his red card in the defeat at Bournemouth and Foxes boss Claude Puel has hinted strongly that he will be replaced by Jonny Evans in the centre of defence.
Puel also suggested that Harry Maguire could be set for a rest, but with one change already necessary at the back it remains to be seen whether that will be the case on Saturday.
Jonathan Hogg will return to contention for Huddersfield. The 29-year-old has served a three-game ban following his dismissal in the recent home draw against Cardiff and boss David Wagner must decide whether the midfielder will start. Defender Erik Durm is available after a back problem.
Ramadan Sobhi remains Wagner's only absentee, with the Egypt international sidelined until after next month's international break due to a knee injury.
Huddersfield squad: Lossl, Kongolo, Schindler, Jorgensen, Lowe, Billing, Hogg, Mooy, Hadergjonaj, Van La Parra, Mounie, Kachunga, Diakhaby, Depoitre, Mbenza, Hamer, Pritchard, Williams, Smith.
Leicester squad: Schmeichel, Ward, Jakupovic, Simpson, Chilwell, Evans, Pereira, Maguire, Fuchs, Gray, Maddison, Albrighton, Amartey, Iborra, Silva, Mendy, Ndidi, Ghezzal, Vardy, Choudhury, Iheanacho, Diabate, Okazaki, Soyuncu.
Liverpool v Southampton - Saturday 3:00pm
Liverpool forward Roberto Firmino is fit to start against Southampton at Anfield. The Brazil international was only a substitute for the Champions League victory over Paris St Germain because of an eye injury sustained against Tottenham last weekend.
Fellow forward Dominic Solanke is back after concussion, Divock Origi (ankle) is set to return to training on Sunday while defender Dejan Lovren (hip) has rejoined the squad but will not feature against Saints.
Southampton must do without on-loan forward Danny Ings for the Premier League trip to Liverpool.
Ings, who has scored three times this season, is ineligible for the match at Anfield under the terms of his season-long switch from the Reds.
Forward Manolo Gabbiadini faces a late fitness test on a hamstring problem picked up in training, but otherwise Saints boss Mark Hughes has no fresh injury worries.
Liverpool squad: Alisson, Alexander-Arnold, Gomez, Van Dijk, Robertson, Wijnaldum, Milner, Keita, Salah, Firmino, Mane, Mignolet, Clyne, Matip, Moreno, Henderson, Fabinho, Shaqiri, Solanke.
Southampton squad: McCarthy, Soares, Vestergaard, Hoedt, Bertrand, Elyounoussi, Lemina, Redmond, Hojbjerg, Long, Austin, Gunn, Yoshida, Targett, Davis, Ward-Prowse, Gabbiadini, Gallagher
Manchester United v Wolverhampton Wanderers - Saturday 3:00pm
Marcus Rashford and Nemanja Matic will miss Manchester United's return to Premier League action against Wolves through suspension.
Rashford serves the second of a three-game ban while Matic will complete a one-match suspension after being sent off at Watford last weekend. Both players started Wednesday's Champions League win at Young Boys, where Antonio Valencia and Jesse Lingard were rested.
The duo are back in contention on Saturday when Phil Jones could return, but Ander Herrera and Marcos Rojo are not fit to be involved. United boss Jose Mourinho confirmed Diogo Dalot will not start despite impressing on his debut in Switzerland and will instead start next week's Carabao Cup match against Derby.
Wolves however are likely to be unchanged for a sixth consecutive Premier League game.
Head coach Nuno Espirito Santo has resisted making alterations to his starting line up so far this season, with club-record signing Adama Traore being used as an impact substitute since his £18million arrival last month.
Portuguese winger Ivan Cavaleiro is expected to be Wolves' only absentee as he continues his recovery from a back injury.
Man Utd squad: De Gea, Romero, Grant, Valencia, Dalot, Darmian, Young, Shaw, Smalling, Jones, Bailly, Lindelof, Pogba, Fellaini, Mata, Pereira, Fred, McTominay, Lingard, Lukaku, Martial, Sanchez
Wolves squad: Patricio, Ruddy, Norris, Doherty, Dendoncker, Bennett, Batth, Enobakhare, Hause, Boly, Coady, Gibbs-White, Jota, Otto, Saiss, Neves, Costa, Moutinho, Vinagre, Bonatini, Traore, Jimenez.
Brighton and Hove Albion v Tottenham Hotspur - Saturday 5:30pm
Pascal Gross remains Brighton's only absentee ahead of Saturday evening's clash with Tottenham.
The German midfielder, who missed Monday's draw at Southampton, is sidelined with an ankle injury sustained against Fulham before the international break.
Winger Jose Izquierdo and forward Florin Andone are awaiting their first appearances of the season after returning to fitness.
Tottenham will assess Dele Alli for the trip to Brighton after he returned to training following a hamstring injury.
Moussa Sissoko (knee) is also back in training but Hugo Lloris (thigh) will again miss out.
Toby Alderweireld and Kieran Trippier will be back in the squad after they were rested at Inter Milan.
Brighton squad: Ryan, Button, Steele, Bernardo, Montoya, Bruno, Bong, Dunk, Duffy, Balogun, Schelotto, Suttner, Bissouma, Stephens, Propper, Kayal, Knockaert, March, Jahanbakhsh, Izquierdo, Andone, Locadia, Murray.
Spurs squad: Vorm, Gazzaniga, Trippier, Walker-Peters, Alderweireld, Vertonghen, Rose, Sanchez, Davies, Dier, Wanyama, Dembele, Eriksen, Lamela, Winks, Moura, Son, Llorente, Kane
West Ham United v Chelsea - Sunday 1:30pm
West Ham manager Manuel Pellegrini is hopeful Marko Arnautovic will be fit to face Chelsea.
Arnautovic was substituted in the second half of West Ham's 3-1 victory at Everton last weekend with a knee problem.
Javier Hernandez (flu) is a doubt, while Jack Wilshere (ankle) is sidelined after surgery. Andy Carroll, Manuel Lanzini and Winston Reid remain long-term absentees.
Meanwhile, Pedro is a major doubt for Chelsea. The Spain winger sustained a shoulder injury in Thursday night's Europa League win at PAOK - a trip Eden Hazard and David Luiz missed.
The rested pair are expected to return against the Hammers, while Mateo Kovacic has a minor injury and may miss out again.
West Ham squad: Fabianski, Adrian, Fredericks, Zabaleta, Ogbonna, Diop, Balbuena, Rice, Cresswell, Masuaku, Obiang, Noble, Sanchez, Antonio, Yarmolenko, Snodgrass, Arnautovic, Perez, Anderson.
Chelsea squad: Kepa, Caballero, Rudiger, Alonso, Fabregas, Jorginho, Kante, Barkley, Hazard, Pedro, Loftus-Cheek, Moses, Giroud, Zappacosta, Willian, Cahill, Christensen, Azpilicueta, Morata, Luiz, Emerson Palmieri, Ampadu, Hudson-Odoi, Bulka.
Arsenal v Everton - Sunday 4:00pm
Unai Emery is likely to recall a number of first-team regulars for Arsenal's clash at home to Everton on Sunday.
The Gunners head coach made eight alterations for Thursday's 4-2 Europa League win over Vorskla Poltava but the likes of Petr Cech, Aaron Ramsey, Mesut Ozil and Alexandre Lacazette will be pushing for returns.
Lucas Torreira took a knock to the knee during the game but Emery hopes he will be fine to face the Toffees, while Laurent Koscielny (Achilles), Sead Kolasinac (knee), Ainsley Maitland-Niles (leg) and Carl Jenkinson (ankle) remain absent.
Everton's joint top-scorer Richarlison returns to the squad following suspension for their trip to the Emirates.
The Brazilian scored three goals in his first two games prior to his sending off against Bournemouth last month. Defender Yerry Mina could come into contention for his debut after a full week of training following a foot problem.
Fellow centre-back Phil Jagielka should be ready to train with the squad again next week following a knee injury but Andre Gomes (hamstring) and Seamus Coleman (foot) remain sidelined.
Arsenal squad: Cech, Leno, Bellerin, Lichtsteiner, Holding, Mustafi, Mavropanos, Papastathopoulos, Monreal, Xhaka, Elneny, Torreira, Guendouzi, Ramsey, Iwobi, Mkhitaryan, Ozil, Welbeck, Lacazette, Aubameyang.
Everton squad: Pickford, Kenny, Holgate, Zouma, Digne, Mina, Schneiderlin, Gueye, Davies, Walcott, Sigurdsson, Calvert-Lewin, Tosun, Richarlison, Stekelenburg, Baines, Browning, Dowell, Niasse, Lookman, Bernard.