Andy Murray and Serena Williams' Wimbledon dream team partnership has come unstuck in the round of 16.
Dubbed 'Murrena', the dynamic duo could not live with the top seeds in the mixed doubles, Bruno Soares of Brazil and American Nicole Melichar, going down in three sets, 3-6, 6-4, 2-6.
It brought to an end Sir Andy's adventure in this year's championship as he battles back to full fitness following hip surgery several months ago.
But for Williams, she still has a semi-final to look forward to on Thursday in the ladies singles tournament.
Following their defeat, the pair said they were pleased with how they had both performed.
Mocking the endless questions Murray gets about his hip surgery and fitness, Williams said: "Andy gets asked every question about his body and the US Open.
"It's great for me because I get to sit here and just look.
"My thing is just to stay focused and not look like I'm daydreaming.
"But it's nice because I love him having all the attention. It's so good. It's such a relief."
Turning to Murray, a chuckling Williams asked: "How is your body?"
When asked if they had plans for the evening, Murray laughed that they did not usually celebrate losing.
But Williams saw the positive side, saying: "We did have a good tournament. I think overall we played really well for our first time to play together."
She added that it was "fun to get to know him". . "It's cool to see people you see on TV and you watch and study - to actually be on the same side as them, to pick their brain a little bit, to help them out, it's a really cool feeling."
On a packed Court No.2, the Murray-Williams team battled back from losing the first set to take the second 6-4.
But they both appeared jaded at the start of the third and deciding set, quickly finding themselves 0-4 down.
It was left to Williams - herself struggling with injuries - to try to save the match, serving at 1-5, which she duly did.
But it was Murray's tame return that he slapped into the net that handed the Soares/Melichar team the win, 6-2 in the third.
That the pairing had made it through two round was remarkable, given they had never played together before this week, and had only hooked up for very limited practice together beforehand.