Video report by ITV News Reporter Natalia Jorquera
Used to seeing clients up close, more than 250,000 people working in the beauty industry are being encouraged to train themselves in the signs of the disease.
The organisation says it gets reports "every week" of skin cancer melanomas from its "army of skin checkers".
Whilst they're not doctors or nurses, they provide a front line defence in fight against the disease.
Anne from Dublin credits her beautician with saving her life after an abnormality was spotted during a routine appointment.
She told ITV News: "During the course of a pedicure, Andrea spotted a mole, which she thought had different colours running through it.
"I went to a dermatologist, who said it need to be exorcised from my foot. It was pre-melanoma and the cells were definitely A-typical.
"Basically if I hadn't had that done, it would have turned into melanoma."
"Yes, it saved my life really," she said.