Elizabeth Warren has dropped out of the Democratic presidential race after a disappointing Super Tuesday result.
The exit comes just days after the one-time frontrunner failed to win a single state in the Super Tuesday vote - when millions vote in 16 states, territories, and groups accounting for almost one-third of the total delegates available in the Democratic nominating contest - including her home state.
The Senator confirmed she was dropping out the race in an address to media and supporters outside her home in Massachusetts.
The two septuagenarians are the leading candidates in the race for the Democratic nomination which now has only three contenders.
Speaking to reporters outside her home, Ms Warren said she would not decide who to endorse on Thursday.
"I need some space and I need a little time right now," she said.
Ms Warren's voice cracked when she talked about meeting so many little girls while campaigning around the country for the past year and knowing they "are going to have to wait four more years", at least, to see a woman in the White House.
At earlier stages in the race, Senator Warren had appealed to progressives within the Democratic Party with her "plan for everything" and strong message of economic populism.
But her initial momentum failed to get results and the Massachusetts Senator became increasingly squeezed out by Mr Sanders - who had an immovable base of voters she needed to advance.
Ms Warren's exit from the race follows a series of other drops outs - beginning in the days before the Super Tuesday vote with Amy Klobuchar and Pete Buttigieg - and most recently billionaire Mike Bloomberg.
Senator Warren made headlines for her stinging attack on Mr Bloomberg - a former New York mayor - when the pair met for the Democratic Debate in Las Vegas.
Elizabeth Warren takes on Mike Bloomberg in the Las Vegas Democratic debate:
The outlook for the remaining Democratic contenders is an unexpected twist for a party that had used the votes and energy of women to retake control of the House, primarily with female candidates, just two years ago.
The Democratic field now has just one female candidate left in contention, Hawaii Representative Tulsi Gabbard, who has collected only one delegate toward the nomination.
Donald Trump, who will face the Democratic nominee in November’s election, wasted little time in taunting the woman he has called "Pocahontas" because of her contested claims of Native American ancestry.
The President has maintained a running commentary over Twitter on the Democratic nominees, with Mr Trump allocating nicknames to more than one of the candidates.