Worldwide nearly 175,000 people have contracted the Covid-19 with the World Health Organisation reporting cases in at least 135 countries, territories or areas.
Here's a rundown of some of the major setbacks across the entertainment industry so far.
The release of Disney's Mulan was postponed the day after stars celebrated at a scaled-back premiere.
Set for release at the end of March, the remake was billed as one of the entertainment giant's blockbuster films of 2020 but has now been delayed until an unspecified date later in the year.
Production on the third instalment of Fantastic Beasts And Where to Find Them has also been postponed while Warner Bros has already halted production on The Batman, starring Robert Pattinson.
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The two groups say they cover "most of the venues in London" - a list on the groups website includes the National Theatre, Shakespeare's Globe, and the Palladium.
In a statement the two groups said: "There are over 290,000 individuals working in the theatre industry across the UK, and the closure of theatres and public venues will have a devastating impact."
New York's theatre district Broadway has fallen silent until at least the beginning of April after gatherings of 500 or more were banned.
Shows are set to remain closed for more than a month, with performances due to resume the week of April 13.
The move effectively forced the hand of theatre producers who had previously said Broadway would "be open for business" unless advised not to by the government.
The theatres are expected to remain closed "until further notice", with the groups saying they were following "government recommendations".
Elsewhere the impacts of the pandemic are being felt across the global music industry too.
Radio 1's Big Weekend will not go ahead, organisers said the decision had been made in order to "prioritise the health and safety of all those involved".
The music festival, which had Biffy Clyro, Harry Styles and Camila Cabello on the line-up, was due to take place in Dundee from Friday May 22 to Sunday May 24.
While Country To Country - one of Europe’s largest country music festivals held across various venues - was postponed less than 24 hours before it was due to begin.
The annual film, music and technology festival, South By Southwest, had been due to take place in Austin, Texas this month but was cancelled in advance.
Teen pop sensation Billie Eilish has been forced to postpone a string of US tour dates as health officials warn against mass gatherings.
"I’m so sad to do this but we need to postpone these dates to keep everyone safe. We'll let you know when they can be rescheduled. Please keep yourselves healthy. I love you."
Other musicians including The Who and Pearl Jam have postponed their tours.
Singer Jamie Cullum also cancelled the remainder of his UK tour ahead of planned performances in cities including London, Oxford, Liverpool and Cardiff.
Several television shows in the United States have reportedly suspended production including NBCUniversal's Law & Order.
In the UK, the production of series six of Peaky Blinders has been halted over fears about the virus, according to the programme's official Instagram page.
Daily talk shows in the US have also been hit - The Tonight Show Starring Jimmy Fallon, Late Night With Seth Myers and The Late Show With Stephen Colbert are all suspending production.
The shows - all filmed in New York - had initially continued with production without a studio audience.
Awards and events
Organisers of awards ceremonies and film festivals have also had to reconsider going ahead with events.
Bafta confirmed the Virgin Media British Academy Television Awards, due to take place on May 17, have been postponed following the coronavirus outbreak.
The LGBTQ awards show, GLAAD Media Awards, set to take place in New York was cancelled. While in London, organisers of announced they were cancelling the event due to the "rapidly evolving Covid-19 pandemic".
The Met Gala - one of the biggest dates in the fashion diary each year - has been postponed, host Anna Wintour confirmed.
The London Book Fair - due to take place at Olympia London - was cancelled with organisers promising it would return next year, "better than ever".
While the city's St Patrick's Day celebrations were cancelled by Mayor Sadiq Khan over coronavirus fears.