With 31 minutes gone, the drone appeared above Brentford’s ground in west London, close to Heathrow Airport.
Referee Peter Bankes and fourth official Martin Atkinson ordered the players off the field in accordance with Premier League rules, with the stadium announcer confirming play had been stopped due to an “unofficial drone”.
Both sets of players looked baffled with Wolves captain Conor Coady asking Bankes “what is going on?”
The teams eventually re-emerged at 3.50pm and had a brief warm-up before play restarted, with 19 minutes of the first half still remaining.
It was the second time the football match was halted in the first half, with a sickening clash of heads between Brentford team-mates Mathias Jensen and Rico Henry which left both bleeding heavily resulted in a lengthy stoppage and the use of concussion substitutes, just minutes before.
Half-time arrived with the score goalless, 71 minutes after the match kicked off.
Wolves took the lead four minutes into the second half through a fine curler from Joao Moutinho.