The UK has fallen behind its European neighbours on cancer survival, dementia deaths and other preventable health problems, a report has found.
Urgent reform was needed to avert "killer" costs and end second-rate care, according to the Institute for Public Policy Research (IPPR) study for its Commission on Health and Prosperity.
Health and social care services have a leading role to play in making the country healthier and "more prosperous" but are currently failing to do so, experts behind the study said.
"The number of deaths that could have been avoided with timely healthcare or public health interventions is much higher in the UK than in all other comparable European nations," the report said.
"We estimate that if the UK had an avoidable mortality rate similar to those in comparable European countries, around 240,000 fewer people would have died in the decade from 2010."
The study puts some of the blame on the inability to access care in a timely way and rising NHS waiting lists.
"Against all logic, in the adult social care market a rising number of requests for care [demand] is being met with a shrinking number finding care providers [supply]," it continued.
Quality of care has also fallen, the report went on, while cancer survival rates remain "stubbornly lower in the UK than in virtually all other rich democracies".
Deaths from dementia are also "radically higher" than in peer countries.
In a 10-point plan, the report said there is a need to prevent future ill-health through creating neighbourhood health hubs to deliver integrated services in every neighbourhood.
A social care guarantee was also proposed, which "delivered by replacing unfair user charges with free personal care and driving up the quality of providers".
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There should also be a new deal for health and care workers, "from better take-home pay to stronger worker rights, to retain and remotivate the workforce".
The IPPR report said the reforms could save taxpayers up to £205 billion over the next decade, adding the annual saving is worth the equivalent of the current UK defence budget by 2033/34.
Former health minister Lord Ara Darzi, who is co-chairman of the IPPR Commission on Health and Prosperity, said: "The NHS and social care system is vital to our individual and national health and prosperity.
"Too many people are struggling to get high-quality care when they need it most. As a result, there are growing calls for us to change our 'free at the point of need' system.
"But now is not the time to abandon the principles which underpin the NHS.
"Instead, we must renew and extend them in order to deliver better health, a stronger economy and a fairer society. This report sets out a plan to achieve this."
The report also warned of the economic impact of long-term sickness on the UK, saying action was needed to reform health and social care.
It said the number of people out of the labour market due to sickness is now at an all-time high of 2.6 million, warning "there is no road to prosperity for this nation without tackling the tide of sickness head-on".
Lord James Bethell, former health minister and commissioner, said: "Sick Britain is costing us our lives, our livelihoods and harming the UK economy.
"If we want to change course, we must stop pretending that the answers are always more hospitals and more acute staff.
"Instead, we must start taking action to reduce demand and need for healthcare, through prevention.
"A mission for a healthy Britain, that targets the concurrent epidemics of obesity, gambling, addiction and online harm, is a precondition for any sustainable, effective national health service in the 21st century."