The mothers of two three year old boys from Norfolk, who have Down's Syndrome, say they have been hurt by people calling them "it".
They are calling for better understanding and acceptance. The two mums have been talking to ITV News Anglia's Natalie Gray.
Norwich Castle will be lit up in blue and yellow from six o'clock tonight to mark World Down Syndrome Day.
The aim of this year's campaign is to celebrate the different ways people with DS bring to their local communities.
And you can find out more about the boys here