It's seen as the biggest and the best if you follow Northampton Town and Peterborough United.
While both clubs have developed rivalries with others in recent seasons, supporters of a certain vintage believe Cobblers v Posh surpasses those alternative derby contests.
Saturday (October 10) will see their first league meeting since Northampton's promotion via the SkyBet League Two play-offs in June.
Before kick-off there will be a minute's silence for Tommy Robson who died 76 after being diagnosed with motor neurone disease.
Managers Keith Curle (Northampton) and Darren Ferguson (Peterborough) set the scene ahead of the contest at the PTS Academy Stadium, giving their pre-match thoughts via Zoom.
Both clubs were boosted by midweek wins in the EFL Trophy. Northampton ran out 5-0 winners against Southampton Under 21s, while Peterborough beat Fulham Under 21s 4-2 on home soil.