The latest official figures show 123 people died with Covid-19 in the Anglia region in the first week of November, the highest number of deaths in week since early June.
Data from the Office of National Statistics (ONS) shows the number of people dying with coronavirus or with the condition mentioned on the death certificate has been increasing in the East of England for seven weeks.
The ONS has released figures for the period up to Friday 6 November. There is a time lag on the information because it is compiled after deaths have been officially registered.
According to separate information published by the Care Quality Commission and the NHS about people dying in care homes and hospitals there have been a further 179 deaths in the area during the period since 7 November.
That includes 35 patient deaths in hospitals in the region announced by the NHS on Tuesday. Eleven patients have died in the past few days at Milton Keynes Hospital with four deaths reported at the Norfolk & Norwich Hospital.
Since the start of the pandemic 6,682 people have died in the Anglia region either with a positive test for Covid-19 or with the condition declared on the death certificate.
The number of people being admitted to hospitals in the Anglia region is also rising.
There were 714 patients admitted to hospitals in the NHS East of England region in the week to 15 November. That was 240 more than the previous week - an increase of 51%.
According to the government's online coronavirus data dashboard there were 810 people in the region's hospitals with Covid-19 and 77 of them were on ventilators.
Across the UK there were 15,830 people in hospital with 1,391 on ventilators.
The Anglia region is the East of England counties of Bedfordshire, Cambridgeshire, Essex, Hertfordshire, Norfolk and Suffolk along with Northamptonshire, Rutland and Milton Keynes