The A595 and A66 in west Cumbria are blocked in both directions after a crash.
It happened at 1:02pm and involved two cars.
Emergency services including air ambulance, police and land ambulance have attended the scene.
Familes have been
Police say the A595 is closed between Papcastle and Fitz Cottage roundabout.
The A66 is also closed at Fitz roundabout in both directions.
The road is expected to be closed for some time while investigations take place.
Vehicles are currently being diverted through Cockermouth.
More information on this story as we get it.