A van has caught fire in lane three of the A74M, half of a mile north of junction 20.
Police and fire services are at the scene and police are asking people to slow down when approaching the incident and to watch the road ahead when passing.
An update has confirmed lane one of three is now open with traffic able to pass the scene.
Police are appealing for witnesses after a van hit a 400 year old cottage in the Lake District causing thousands of pounds worth of damage.
A white van was caught on a neighbour's CCTV camera reversing towards the property before driving away. It happened at around 3 o'clock on Thursday afternoon at Laurel Cottage Bed and Breakfast in Bowness-on-Windermere.
The building is a converted 16th-century school which suffered damage to its low-lying rear roof and a wall.