An outbreak of bovine TB has been confirmed in the Brampton area of north Cumbria.
There are restrictions in place when it comes to moving affected cattle and farms within a three kilometre radius will also be tested.
The NFU has advised farmers to be careful when bringing animals into the county by looking at their sourcing policy and where animals are coming from.
Cumbria is a low risk area on the border of Scotland - which has a TB free status.
More top news
Star-studded lineup for this year's Kendal Calling as Cumbria's biggest music festival celebrates its fifteenth anniversary.
The full-scale replica was used in the recent Hollywood adaptation of Agatha Christie's Murder on the Orient Express.
The A66 is closed in both directions near the Cumbrian border with County Durham.