Traders in Dumfries say 18 businesses have closed in the past four months.
This week Scottish Enterprise announced it was starting a service in Dumfries and Galloway to support retailers.
But traders in the town say that without urgent help, the situation is likely to get worse.
I think it's very close to becoming a ghost town, as are all small towns in Scotland now.
They are all on the edge of disaster. We are not doing enough to make it easier to shop in the town centre.
We are standing in a big pedestrianised area, people like their cars to go shopping, but they can't take their car anywhere near our town centre because there's just no access.
More top news
Emma brings you Saturday's forecast
Fell runner Joss Naylor has completed the Lake District Mountain Trial race he failed to finish 57 years ago raising money for Brathay.
Cumbria Constabulary, is teaming up with other police forces in the UK to prevent weapons from getting into the wrong hands.