Transpennine Express has warned travellers that services between Lockerbie and Edinburgh will be disrupted due to Storm Doris.
Trains may be severely delayed or cancelled altogether as snow and flooding hit Scotland.
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Downing Street said Foreign Secretary Dominic Raab would "deputise where necessary" while the PM was in intensive care with Covid-19.
High pressure brings more settled weather this week.
A Workington couple hosted a virtual wedding ceremony after their big day was postponed due to the coronavirus outbreak.