A freight train derailment near Sheffield is causing major disruption to passenger services
Several wagons came off the tracks at 0245, according to Network Rail. No other trains were involved.
National Rail Enquiries said "disruption is expected until at least the end of today".
Affected operators are CrossCountry, East Midlands Railway, Northern and TransPennine Express. All lines through Sheffield are blocked, with services cancelled, delayed and diverted.
Northern said it is "working to put alternative road replacement transport in place".
It is not known what the derailed train was carrying.
Network Rail said nobody was hurt, but the incident has led to significant damage to signalling and points equipment, which means five of the station’s eight platforms are closed.
Three platforms have been made available to enable a very limited service to run, but this means a significant number of unavoidable cancellations, with other services subject to severe disruption.
Officials from the Rail Accident Investigation Bureau will examine the scene before the train can be removed.
We’re really sorry about the huge amount of disruption that will be caused to passengers today. We will have our people working around the clock to get the station fully reopened as quickly as possible, but it’s going to be a complex problem that won’t be resolved immediately.