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The A633 Warren Vale is closed northbound between Kilnhurst Road and B6090 Wentworth Road.
Two lanes are closed and there is queueing traffic due to a broken down vehicle on the M621 westbound between J7 A61 (Stourton) and J6 (Belle Isle Road).
There is stationary traffic due to an accident and a rolling road block is in place on the M62 Westbound between J24 A629 (Ainley Top) and J23 A640 / A643 (Huddersfield)
The A1 Northbound is closed due to accident between A6136 Leeming Lane (Catterick South) and A6136 Gatherley Road (Catterick North).
The A180 in Grimsby into town partially blocked due to shed load of fish between Birchin Way/Pyewipe Road/Moody Lane and the A16 Victoria Street North/A180 Cleethorpe Road/Lockhill.
There are reports that seagulls picking at the fish are causing an additional hazard.
A car has overturned on the M62 eastbound in West Yorkshire this morning.
One lane is blocked due to the incident at junction 27 for Gildersome near the exit for the M621, although traffic is reportedly still flowing.
Commuters are being warned that the incident is likely to affect drivers heading towards the M1.
A major route into Leeds is expected to be disrupted for several hours this morning after a crash involving two vehicles and a building.
Officers from West Yorkshire Police have closed the A65 Kirkstall Road in both directions after the incident left two people seriously injured.
Roads in the area are expected to be closed during rush hour.
Latest ITV News reports
Emergency services have not yet confirmed how many people have died in the collision, which happened just before 1am.
The roads around Yorkshire's tallest building are expected to remain shut until 10am.