There is very slow traffic and one lane is closed due to an accident on the M62 westbound between J28 A650 / A653 (Tingley) and J27 M621 / A650 / A62 (Gildersome). Lane one (of three) is closed.
Emergency services have not yet confirmed how many people have died in the collision, which happened just before 1am.
The roads around Yorkshire's tallest building are expected to remain shut until 10am.
The M1 is shut northbound J42 at Lofthouse, causing congestion on the M1 to J39 A636 (Wakefield / Durkar).