An investigation by ITV News Central has found that the number of nurses taking time off because of stress has increased in the Midlands.
For the East Midlands, it has gone up by 30%, and for the West Midlands, 39%, between 2011 and 2015.
Sandra Humberstone works as a lung cancer nurse at City Hospital in Nottingham. She says the job is both emotionally and practically challenging:
Sandra said a running club organised by the hospital's health and wellbeing department has helped her cope.
Steph Knowles, who organises the club, says it is important to look after hospital staff to help them perform at their best:
Dr Sheila Marriott, who represents the Royal College of Nursing in Nottinghamshire, believes the problem is largely due to a national shortage of nurses.
She say nurses are often "too overstretched to deliver the quality of care they want to achieve."
Some hospital trusts are recruiting nurses from abroad to try and fill the gap.
The trust that looks after hospitals in Leicester, University Hospitals of Leicester NHS Trust, wants to recruit around 300 hospital jobs from countries like India and the Philippines.
The first 30 recruits will start next spring:
The nurses we spoke to in the course of this investigation all agreed that the job has got busier. They cited reasons like higher patient expectations, an ageing population and a general increase in workload.
Hospital trusts also told us that they are actively encouraging nurses to report stress related absences, and this could also have contributed to the increase.