Birmingham is on the final shortlist to be the location of Channel 4's new national headquarters.
Coventry, Stoke-on-Trent and Nottingham, which were all initially part of the bid, failed to be selected.
The broadcaster plans to move 300 staff and hundreds of millions of pounds of TV programming out of London.
It will be the biggest structural shake-up in the 35-year history of the channel.
Greater Manchester and Leeds have also made the final shortlist to either be the National HQ or one of two "creative hubs".
Bristol, Cardiff and Glasgow are also in the running to be creative hubs.
The locations for the new headquarters and the two creative hubs will be announced in the autumn.
We have again had to take some very difficult decisions on which cities to take forward to the next stage, but we believe the six cities we have selected are best able to deliver against our vision and requirements for the new National HQ and Creative Hubs.
Andy Street, Mayor of the West Midlands, tweeted to say he was "disappointed" Coventry was not selected, but called on the region to "get behind Birmingham".
George Duggins, Leader of Coventry City Council, said he was "naturally disappointed" the city was out of running.
However, he said the "next best choice" would be to "select a location in the vicinity" - and backed Birmingham's bid.
We are naturally disappointed at today’s announcement.
The Deputy Leader of Stoke-on-Trent City Council says the city failed to reach the final stages due to a lack of sufficient "creative infrastructure".
We are hugely disappointed, but the whole bidding team could not have produced more of a compelling pitch to put forward our city’s case.