Around 100 homes and some businesses had to be evacuated overnight after a fire broke out at a commercial garage in Normanton.
Firefighters were called to Twyford Street just before 7pm on Saturday 10 November.
Properties were also evacuated on Harriett Street, Grove Street, Twyford Street and some businesses have also been evacuated on Normanton Road.
A refuge centre was set up up St Augustine's Church on Upper Dale Road for people to spend the night.
Normanton Road, Twyford Street, Harriet Street and Grove Street remain closed.
Sean Wells, Group Manager from Derbyshire Fire and Rescue Service, said: “A decision was taken to evacuate people living and working on several roads surrounding the fire due to the presence of commercial cylinders.
“A refuge centre has been set up for those evacuated at St. Augustine’s Church, Upper Dale Road, DE23 8BP where they can seek shelter until the incident is resolved.
“We are working with our emergency service partners and the emergency planning team, and as soon as we are satisfied that the cylinders have been isolated and pose no risk to residents, we will let residents know that they are able to return to their homes.”