Huge clouds of smoke can be seen coming from the fire, and locals are being urged to keep their windows and doors closed, while they tackle the flames.
Two people who were staying on site are being treated by East Midlands Ambulance service for smoke inhalation.
14 fire engines and an Aerial Ladder Platform (ALP) are at the scene. Crews are being assisted by Derbyshire Fire and Rescue Service.
Nottinghamshire Fire and Rescue say large crowds are now gathering near the fire, and are urging people to stay away from the area for their own safety as crews continue to arrive and tackle the fire.
Area Manager Andy Macey, the incident commander, said: "Thank you to our partners in Derbyshire, Lincolnshire and South Yorkshire fire and rescue services for their support.
"We ask the public not to gather near the scene as they put themselves at risk and hinder us in our work.
"We are likely to be on scene for some time so we thank the public for their patience."