Wolves face their biggest challenge of the FA Cup so far this season when they host Premier League leaders Chelsea at Molineux in the fifth round.
Manager Paul Lambert says he expects formidable opposition on Saturday but a fantastic atmosphere.
Two of the remaining Midlands teams left in the fifth round of the FA Cup have both drawn Premier League opposition.
Non-league Lincoln City have drawn Burnley, while Wolverhampton Wanderers will face Chelsea.
Meanwhile, either Derby County or Leicester City will face Milwall following their fourth round replay.
Ipswich Town v Lincoln/Oldham
Wigan v Nottingham Forest
Birmingham City v Newcastle
Chelsea v Notts County/Peterborough
West Bromwich Albion v Derby County
Everton v Leicester City
Wycombe v Northampton Town/Stourbridge
Watford v Burton Albion
Stoke City v Wolverhampton Wanderers
Bristol City v Shrewsbury Town/Fleetwood
Huddersfield v Port Vale
Tottenham v Aston Villa
The FA Cup Second Round clash between Northampton Town's and Stourbridge has been postponed.
The decision was made around 12.15pm because of a frozen pitch.
Referee Andy Davies checked the conditions upon his arrival and found parts of the War Memorial Ground to be frozen.
No new date has yet been confirmed for the game, but supporters are asked to keep their tickets safe until a new date is confirmed.
See who our teams in the Midlands drew for the second round of the FA Cup.Read the full story ›
It was the biggest game in Shrewsbury Town's history this evening as they hosted Manchester United but they suffered a 3-0 defeat against the Premier League giants.
They took the lead after half an hour when Chris Smalling volleyed in and the visitors scored again in first half added time with a free kick from Juan Mata.
They made sure of the result in the second half with another goal from Jesse Lingaard.
Abu Agogo had the Shrews' best chance with a free header late on but they could not find a response to Louis Van Gaal's men.
Shrewsbury now turn their attentions to avoiding relegation from League one.
League One Shrewsbury Town will host Manchester United in the fifth round of the FA Cup later tonight.
It's the first time the two sides have ever met in a competitive fixture.
Melissa Wright looks ahead to tonight's match.
League One side Shrewsbury Town host Manchester United in the fifth round of the FA Cup tonight.
Manager Micky Mellon insists his players won't be intimidated by the opposition and will enjoy the game:
Shrewsbury boss Micky Mellon believes his side must execute their plan perfectly to beat Manchester United.Read the full story ›
Aston Villa welcome Manchester City this weekend in the fourth round of the FA Cup.
Manager Remi Garde says his side are in a good place at the moment, after going unbeaten in five.
One dedicated fan who travels almost 400 miles to watch every home game is backing Villa to win.
Melissa Wright reports.