The Duchess of York will be among the guests opening a new children's cancer and neurosciences ward and teenage cancer trust unit at Nottingham Children's Hospital today.
The development has cost £4.7 million and has been part funded by the Teenage Cancer Trust of which Sarah, Duchess of York is a patron.
As Nottingham Children's Charity launches an appeal to raise £500k for the city's Children's Hospital, medical staff have explained why the centre is in need of updating.
Professor Richard Grundy, said:
"The unit is out-dated. It has been the same ward for at least 20-years and times have moved on, things are wearing out. What we want is a brighter, better, safer environment for children facing life-threatening illnesses."
Nottingham Hospitals Charity has launched an appeal to raise half-a-million-pounds for the city's Children's Hospital.
The money will be used to upgrade wards, provide space and facilities for parents to stay overnight and on an improved ventilation system to reduce the risk of infection.