Clarence Mitchell the spokesman for Kate and Gerry McCann, say they believe Madeleine is still alive and feel positive when they see the image that has been released by the Metropolitan Police.
The e-fit image shows what Madeleine would look like now.
Our correspondent Gareth Owen has revisited Praia da Luz, five years since the disappearance of Madeleine McCann.
A timeline of events on how the investigation into Madeleine McCann's disappearance has elapsed over the 5 years since she went missing.
The parents of Madeleine McCann have spoken about the investigation into their daughters disappearance in a TV interview.