The Rutland & Melton MP Alan Duncan has released a statement to say he is standing down from the government as his own request.
He said: "I have been privileged to spend four years as Minister for International Development, which has been one of the most fulfilling responsibilities I have assumed in my life.
"I am proud to have contributed to Britain's role in the world, but am now looking forward to weighing in behind the government's domestic efforts to restore the UK's economic fortunes."
Loughborough MP Nicky Morgan says she is "very excited" to be the new Education Secretary, replacing Michael Gove in the Cabinet reshuffle.
The 74-year-old told ITV News that he spent more time at the cricket test match last week than in his office.
Which female MPs from the Midlands could make it into the cabinet?