The M60 motorway has been shut in both directions near Denton after a woman fell from an overhead bridge.
The stretch of carriageway between junction 24 for Hyde - near its connection with the M67 - and junction 25 for Bredbury has been shut while emergency crews work at the scene.
Police said the woman is being treated by paramedics after she fell at around 4.30pm.
Motorists have been urged to avoid the M60 around Tameside .
A tweet from Greater Manchester Police's official feed at 5.09pm said: