Large accessible toilets for severely disabled people - known as Changing Places - will be made compulsory for new buildings in England from 2021.
Shopping centres, supermarkets, sports and arts venues will be required to include at least one Changing Place, a government spokesman said.
The facilities include hoists, changing benches and space for carers.
Campaigner Zack Kerr said the announcement was "nothing short of life changing".
A government spokesman said there were more than 1,400 Changing Places toilets in the UK, compared with 140 in 2007, but more were needed to support about 250,000 severely disabled people.
Read the full government response here