Rail networks across all parts of the North West are expected to run with severe disruption due to strikes.
The strike, which is the biggest by rail workers for a generation, are causing the cancellation of about 80% of train services across the country.
Thousands of members of the Rail, Maritime and Transport (RMT) union at Network Rail and 13 train operators will walk out on Tuesday, Thursday and Saturday.
Disruption will also continue into Wednesday, Friday and Sunday as the knock-on effects from signallers and control room staff who usually work overnight are felt.
It comes after a bitter dispute over pay, jobs and conditions, with all sides blaming each other for the lack of progress.
Passengers needing to travel are being urged to plan ahead and are warned not to travel unless absolutely necessary on strike days.
Disruption to services on Wednesday 22 June, Friday 24 June and Sunday 26 June will also be felt by passengers as trains will leave depots later than normal, delaying the start of services.
Network Rail expects a limited number of trains to run on following services:
Avanti West Coast
A significantly reduced timetable will be in place on the three days
Services from London Euston will run every hour to Manchester, Liverpool, Birmingham and Preston
Blackpool will have no Avanti West Coast services on strike days
There are no direct trains from London to Chester on strike days
Trains will not be calling at Stockport, Macclesfield, Stoke-on Trent or Runcorn, and these stations will be closed.
Customers with existing tickets for travel from Tuesday to Sunday can get a refund with further sales suspended to help reduce disruption and overcrowding
For more information on other destinations, check the Avanti West Coast website.
Just one train per hour is expected to run between Birmingham New Street and Manchester Piccadilly
They are warning of last minute changes to the timetable
London Northwestern Railway
No trains will operate between London Euston and Crewe
There will be no train services and no rail replacement buses on strike days
Services will not be operating on most routes, with a very limited number of trains on the few running lines
Most services will see a significant reduction of trains
There will also be significant disruption on Wednesday and Friday
Greater Manchester Metrolink
Metrolink services will continue to operate on Tuesday 21, Thursday 23 and Saturday 25 June.
All lines will run to their usual frequency and times, except the Altrincham line, with the information detailed below.
There will be additional double services across the network on the affected dates in order to create extra capacity on the network.
More information can be found here.